Emergence of serotype 10A-ST11189 among pediatric invasive pneumococcal diseases, South Korea, 2014-2019

This study analyzed changes in serotype distribution through serotyping, multilocus sequence typing, and antimicrobial susceptibility testing of 168 pediatric IPD isolates obtained from a multihospital-based surveillance system during 2014-2019 in South Korea. Vaccine serotypes (VTs) accounted for 16.1% (19A, 10.1%; 6A, 1.8%; and 19F 1.8%), 82.1% were NVTs (10A, 23.8%; 15A, 8.3%; 12F, 6.5%; 15C, 6.5%; and 15B, 6.0%), and three (1.8%) were nontypeable. Serotype 10A was the most common serotype, with a significant increase from 11.5% in 2014 to 33.3% in 2019 (p < 0.05 for the trend). Other NVTs decreased from 70.4% to 41.7% between 2015 and 2019, most notably in serotype 12F (from 14.8% to 0%). Almost all (95.0%) serotype 10A isolates were ST11189, which were multidrug resistant.PMID:34465475 | DOI:10.1016/j.vaccine.2021.08.072

Source: Vaccine - September 1, 2021 Category: Allergy & Immunology Authors: Ki Wook Yun Kyuyol Rhie Jin Han Kang Kyung-Hyo Kim Jong Gyun Ahn Yae-Jean Kim Byung Wook Eun Sung Hee Oh Hye-Kyung Cho Young Jin Hong Nam Hee Kim Yun-Kyung Kim Hyunju Lee Taekjin Lee Hwang Min Kim Eun Young Cho Chun Soo Kim Su Eun Park Chi Eun Oh Dae Sun Source Type: research