Demethylzeylasteral (T-96) initiates extrinsic apoptosis against prostate cancer cells by inducing ROS-mediated ER stress and suppressing autophagic flux

CONCLUSIONS: Taken together, our data demonstrated that T-96 is a novel modulator of ER stress and autophagy, and has potential therapeutic applications against CaP in the clinic.PMID:34488902 | DOI:10.1186/s40659-021-00350-6

Source: Cell Research - September 7, 2021 Category: Cytology Authors: Dong-Lin Yang Ya-Jun Zhang Liu-Jun He Chun-Sheng Hu Li-Xia Gao Jiu-Hong Huang Yan Tang Jie Luo Dian-Yong Tang Zhong-Zhu Chen Source Type: research