Head-to-Head Comparison of 68Ga-Prostate-Specific Membrane Antigen PET/CT and Ferumoxtran-10-Enhanced MRI for the Diagnosis of Lymph Node Metastases in Prostate Cancer Patients

Conclusion: Both modalities identified suspicious LNs that were missed by the other. Both modalities identified suspicious LNs in all anatomic regions of the pelvis; however, nano-MRI appeared to be superior in detecting smaller suspicious LNs. These findings suggest that nano-MRI has a potential role as a complement to PSMA PET/CT. However, since the clinical implications of the different results are not well established yet, further investigation of this complementary use is encouraged.

Source: Journal of Nuclear Medicine - September 2, 2021 Category: Nuclear Medicine Authors: Schilham, M. G. M., Zamecnik, P., Prive, B. M., Israel, B., Rijpkema, M., Scheenen, T., Barentsz, J. O., Nagarajah, J., Gotthardt, M. Tags: Clinical Source Type: research