Sex dependent glial-specific changes in the chromatin accessibility landscape in late-onset Alzheimer ’s disease brains

In the post-GWAS era, there is an unmet need to decode the underpinning genetic etiologies of late-onset Alzheimer ’s disease (LOAD) and translate the associations to causation.

Source: Molecular Neurodegeneration - August 24, 2021 Category: Neurology Authors: Julio Barrera, Lingyun Song, Julia E. Gamache, Melanie E. Garrett, Alexias Safi, Young Yun, Ivana Premasinghe, Daniel Sprague, Danielle Chipman, Jeffrey Li, H élène Fradin, Karen Soldano, Raluca Gordân, Allison E. Ashley-Koch, Gregory E. Crawford and O Tags: Research article Source Type: research