O-005 Mullerian anomalies overview

Abstract textMullerian Duct Anomalies- An OverviewProf. Sudha PrasadPresident Indian Fertility Society, Director, Matritava Advanced IVF& Training Centre, New Delhi, IndiaCongenital anomalies of the mullerian duct system is one of the complex disorder encountered in gynecological practice. Mullerian ducts are paired embryological structures which undergo fusion and resorption in utero to form the uterus, fallopian tubes, cervix and upper two-thirds of the vagina. Disruption in the mullerian duct development throughout embryogenesis could result a large spectrum of inherent abnormalities identified as mullerian duct anomalies (MDAs).There is a wide variation in the prevalence of MDAs across various studies, ranging from 1 –10% in the general population to 2–8% among infertile women and 5–30% among women with a history of miscarriage. These discrepancies in the reported prevalence are mainly attributed to lack of a universal classification system.Different varieties of malformations can occur when this system is not well developed. It ranges from absence of uterus, cervix or vagina, septum/duplication of vagina to of the uterus and vagina to minor uterine cavity abnormalities. Mullerian malformations are frequently associated with abnormalities of the renal and axial skeletal systems. Therefore, on initial examination of MDAs patients, these points should be kept in mind.Most mullerian duct anomalies (MDAs) are associated with functioning ovaries and age-appropriate e...
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research