P –590 Women with hypothalamic hypogonadism have lower live birth rates following frozen embryo transfer

This study is limited by its retrospective nature and the small sample size of women with hypothalamic hypogonadism. Additionally, these data represent outcomes from a single academic center, so generalizability of our findings may be limited.Wider implications of the findings: Lower live birth rates for HH patients undergoing frozen embryo transfer cycles are not correlated with endometrial stripe thickness. This may be due to absent gonadotropin signaling on endometrial receptors. A prospective randomized trial of HH patients to modified natural versus programmed frozen embryo transfer would best support this hypothesis.Trial registration numberNot applicable
Source: Human Reproduction - Category: Reproduction Medicine Source Type: research