Advancing intraoperative magnetic tracing using 3D freehand magnetic particle imaging
ConclusionfhMPI is feasible in vivo, providing 3D imaging and navigation for magnetic nanoparticles in the operating room, expanding the guidance possibilities during magnetic sentinel lymph node procedures. Furthermore, the integration of ICG provides the ability to visually refine and confirm correct localization. Further clinical evaluation should verify these findings in human patients as well.
A 69-year-old Caucasian man with no personal or family history of skin cancer presented with a 15-month history of an enlarging 2.5 × 2.3 cm ulcerated, irregularly brown pigmented lesion with a central whitish-blue nodule on the distal right penis shaft without groin adenopathy. Diagnostic biopsy demonstrated invasive melanoma. Excision demonstrated invasion to 1.76 mm, 3 mitoses per mm2, melanoma in situ (MIS) at the margins. Bilateral inguinal lymph node biopsies were negative. Given the Breslow depth and residual MIS, urology and surgical oncology recommended definitive removal via penectomy.
Conclusions: Glans resurfacing is an emerging new appealing surgical technique that is already a recommendation in the EAU guidelines for the treatment of premalignant and superficial penile lesions. The overall satisfaction rate and recovery of the sexual function are acceptable, and it can be considered an ideal procedure to treat superficial penile cancer. PMID: 31312658 [PubMed - indexed for MEDLINE]
CONCLUSIONS: We report the initial feasibility of intraoperative confocal laser endomicroscopy for penile cancer optical biopsy. Pending further evaluation, confocal laser endomicroscopy could serve as an adjunct or replacement to conventional frozen section pathology for management of penile cancer. PMID: 31537485 [PubMed - as supplied by publisher]
ConclusionPenile cancer is a rare but significant disease in Rwanda. Patients present with advanced disease. After treatment of the primary tumor, modified inguinal lymphadenectomy appears to be a safe method of cure and staging for patients with clinically impalpable inguinal lymph nodes. Our early results provide a compelling insight into this rare but serious disease.
ConclusionWith ICG-99mTc-nanocolloid, the SN biopsy procedure has become more accurate and independent of the use of blue dye. With that, the procedure has evolved to be universal for different malignancies and anatomical locations.
Conclusion: To address the many challenges posed by EDCs, we argue that Africans should take the lead in prioritization and evaluation of environmental hazards, including EDCs. We recommend the institution of education and training programs for chemical users, adoption of the precautionary principle, establishment of biomonitoring programs, and funding of community-based epidemiology and wildlife research programs led and funded by African institutes and private companies. https://doi.org/10.1289/EHP1774 Received: 16 February 2017 Revised: 22 May 2017 Accepted: 24 May 2017 Published: 22 August 2017 Address correspond...
ConclusionsThe addition of SPECT/CT improved the rate of detection of true tracer-avid lymph nodes and delineated their precise (3-D) anatomic localization in drainage basins.
Patient admitted with anxiety regarding a nonspecific skin lesion localized to the genital region. There is no pain or erythema. The lesion is localized to the glans penis and is appears purple. Light shone at the lesions reveals whitish streaks. The patient has state insurance Medicaid, and you wish to perform a biopsy to rule out cancer. The patient stated he has to wait 3-5 weeks to obtain a derm appointment, however is very anxious about the lesion. Do you call for a derm consult to... Question about ER procedure
About a year ago, I entered trauma therapy. For the first time I was honest with myself about the sexual abuse I experienced as a child. It opened a floodgate and shame, disgust, resentment, and depression rushed in. I’m happy to say that today those feelings are lessened or absent completely. I started working out a lot and traded a lot of fat for muscle. Every inch of me is now shaped differently. I’m the fittest and strongest I’ve ever been in my life. And yet I’m also sick. The stress of the past year did a number on my body. I was recently diagnosed with cervical intraepithelial neoplasia ...
We report our experience with clinical follow up of men with biopsy proven penile LS at a large academic practice to evaluate the risk of developing cancer at a later time.