Systemic burden and cardiovascular risk to Porphyromonas species in apical periodontitis

ConclusionsAP and infection withP. endodontalis positively associated with cardiovascular risk based on hsCRP levels and endotoxemia, respectively, whereas anti-P. endodontalis IgG response seems to be protective against low-grade systemic inflammation.Clinical relevanceApical periodontitis and endodonticP. endodontalis can influence the systemic burden with impact on the surrogate cardiovascular risk marker hsCRP, providing mechanistic links.
Source: Clinical Oral Investigations - Category: Dentistry Source Type: research