Dopaminergic brainstem disconnection is common to pharmacological and pathological consciousness perturbation [Neuroscience]

Clinical research into consciousness has long focused on cortical macroscopic networks and their disruption in pathological or pharmacological consciousness perturbation. Despite demonstrating diagnostic utility in disorders of consciousness (DoC) and monitoring anesthetic depth, these cortico-centric approaches have been unable to characterize which neurochemical systems may underpin consciousness alterations. Instead, preclinical...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Neuroscience Biological Sciences Source Type: research