Overexpression of MRP3 in HeLa-UGT1A9 Cells Enhances Glucuronidation Capability of the Cells

CONCLUSION: The newly engineered HeLa-UGT1A9-MRP3 cells are an appropriate model to study the kinetic interplay between multiple UGTs and efflux transporters. It's a promising biosynthetic tool to obtain flavonoids glucuronides of high purity.PMID:34279197 | DOI:10.2174/1389200222666210716151520

Source: Current Drug Metabolism - July 19, 2021 Category: Drugs & Pharmacology Authors: Qiong Zhou Bijun Xia Taijun Yin Yu He Ling Ye Ming Hu Source Type: research