Plumbagin can potently enhance the activity of xanthine oxidase: in vitro, in vivo and in silico studies

CONCLUSION: In summary, this study outlines a potential source of toxicity for PLB due to the powerful enhancement of XO activity, which may provide the crucial reminding for the PLB-containing preparation development and clinical application.PMID:34274011 | DOI:10.1186/s40360-021-00511-z

Source: BMC Pharmacology and Toxicology - July 18, 2021 Category: Drugs & Pharmacology Authors: Liang Yue Nan Jiang Anguo Wu Wenqiao Qiu Xin Shen Dalian Qin Hong Li Jing Lin Sicheng Liang Jianming Wu Source Type: research