Targeting cPLA2 α inhibits gastric cancer and augments chemotherapy efficacy via suppressing Ras/MEK/ERK and Akt/β-catenin pathways

ConclusionsOur work demonstrates cPLA2 α inhibition as a therapeutic strategy to overcome chemo-resistance and highlights the association of cPLA2α and Ras in gastric cancer.

Source: Cancer Chemotherapy and Pharmacology - July 13, 2021 Category: Cancer & Oncology Source Type: research