A systematic review of neurocognitive dysfunction with overactive bladder medications

ConclusionIn this review, cognitive decline was reported with oxybutynin and tolterodine use and should be used with caution in adults over 65  years of age. Solifenacin, fesoterodine, and imidafenacin showed mixed results related to central nervous system effect. Trospium and darifenacin were not associated with cognitive decline among patients with and without baseline cognitive impairment.
Source: International Urogynecology Journal - Category: OBGYN Source Type: research