Oral transmucosal absorption of iodine after intraoral preparation with povidone-iodine prior to oral surgeries: a randomized controlled study in 12 male patients

Conclusion(s)Oral transmucosal absorption of iodine is observed when povidone-iodine is used for intraoral preparation in healthy male adults, though the free thyroxine in blood is not affected accordingly.Clinical relevancePovidone-iodine is commonly used as an antiseptic in oral surgery and dental clinics. Based on our findings that iodine levels in blood and urine may elevate significantly after intraoral preparation with povidone-iodine prior to oral surgeries, care must be taken for individuals when excess iodine intakes can endanger the safety of the patient.Registration informationName of the trial registry: The Chinese Clinical Trial Registry (http://www.chictr.org.cn/). Registration number: ChiCTR2100042028
Source: Clinical Oral Investigations - Category: Dentistry Source Type: research