Improving analysis practice of continuous adverse event outcomes in randomised controlled trials - a distributional approach

ConclusionWhen dichotomisation of continuous adverse event outcomes aids clinical interpretation, we advocate use of a distributional approach to retain statistical power. Methods are now easy to implement. Retaining information is especially valuable in the context of the analysis of adverse events in RCTs. The routine implementation of this automated approach requires further evaluation.
Source: Trials - Category: Research Source Type: clinical trials