An Integrated Management Paradigm for Skull Base Chordoma Based on Clinical and Molecular Characteristics

Conclusion Genotypic grouping by 1p36 and homozygous 9p21(p16) deletions can predict prognosis in SBC and guide management. GTR remains the cornerstone of SBC treatment and can be sufficient without AdjXRT in low and intermediate risk tumors. Low-risk tumors are associated with a less invasive phenotype, which makes them more amenable to GTR. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text

Source: Journal of Neurological Surgery Part B: Skull Base - June 22, 2021 Category: Neurosurgery Authors: Abdallah, Hussein M. Gersey, Zachary C. Muthiah, Nallammai McDowell, Michael M. Pearce, Thomas Costacou, Tina Snyderman, Carl H. Wang, Eric W. Gardner, Paul A. Zenonos, Georgios A. Tags: Original Article Source Type: research