Lipoprotein(a) levels and atherosclerotic plaque characteristics in the carotid artery: The Plaque at rISK (PARISK) study

Lipoprotein(a) is an independent risk factor for cardiovascular disease and recurrent ischemic stroke. Lipoprotein(a) levels are known to be associated with carotid artery stenosis, but the relation of lipoprotein(a) levels to carotid atherosclerotic plaque composition and morphology is less known. We hypothesize that higher lipoprotein(a) levels and lipoprotein(a)-related SNPs are associated with a more vulnerable carotid plaque and that this effect is sex-specific.

Source: Atherosclerosis - June 10, 2021 Category: Cardiology Authors: Dianne H.K. van Dam-Nolen, Anouk C. van Dijk, Genevi ève C. Crombag, Carlo Lucci, M. Eline Kooi, Jeroen Hendrikse, Paul J. Nederkoorn, Mat J.A.P. Daemen, Antonius F.W. van der Steen, Peter J. Koudstaal, Florian Kronenberg, Jeanine E. Roeters van Lennep, Source Type: research