Maintenance of cellular annexin A1 level is essential for PI3K/AKT/mTOR-mediated proliferation of pancreatic beta cells

This study identified a positive correlation between AnxA1 protein and pancreatic β-cell proliferation. AnxA1 protein expression might affect the proliferation of MIN6 cells via regulation of cyclin D1, cyclin E, and CDK2 proteins, as well as the PI3K/Akt/mTOR signaling pathway.PMID:34092075 | DOI:10.23812/20-417-A
Source: Journal of Biological Regulators and Homeostatic Agents - Category: Biomedical Science Authors: Source Type: research