Dual HER2 Gene Protein Assay: Focused Study of Breast Cancers With 2+ Immunohistochemical Expression.
CONCLUSIONS: Although GPA is an alternative to both IHC and FISH, it may be an unnecessary test for IHC 0/1+/3+ cases. The clinical utility of GPA appears to be similar to other in situ hybridization assays (ie, adjudicator of HER2 status for IHC 2+ cases).
PMID: 25696805 [PubMed - in process]
Source: Clinical Breast Cancer - Category: Cancer & Oncology Authors: Li Z, Dabbs DJ, Cooper KL, Bhargava R Tags: Am J Clin Pathol Source Type: research
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