Presence of interferon- λ 4, male gender, absent/mild steatosis and low viral load augment antibody levels to hepatitis C virus

CONCLUSIONS: To our knowledge, this is the first report that demonstrates that the ability to produce IFN-λ4, in addition to male gender, absent/mild steatosis, and lower viral load, augments antibody levels against HCV. This indicates that IFN-λ4 may be associated with T helper cell 2 (Th2) immune skewing, which might have clinical implications beyond HCV infection. ClinicalTrials.gov Identifier: NCT00143000.PMID:34078234 | DOI:10.1080/00365521.2021.1922750

Source: Scandinavian Journal of Gastroenterology - June 3, 2021 Category: Gastroenterology Authors: Jesper Waldenstr öm Kristoffer Hellstrand Johan Westin Staffan Nilsson Peer Christensen Martti F ärkkilä Kristine M ørch Nina Langeland Gunnar Norkrans Martin Lagging Source Type: research