Improving Survival in Lymphangioleio ­myomatosis: A 16-Year Observational Study in a Large Cohort of Patients

Conclusions: We provide the data supporting the long-term efficacy of sirolimus therapy in a large cohort of patients with functional impairment and other manifestations of the disease. Our results also suggest that the advent of sirolimus and the publication of international guidelines changed the natural history of the disease lowering the mortality and reducing the need of invasive diagnostic techniques.Respiration
Source: Respiration - Category: Respiratory Medicine Source Type: research