Meta-Analysis of Duration of Dual Antiplatelet Therapy in Acute Coronary Syndrome Treated With Coronary Stenting

We aimed to evaluate if a shorter course of DAPT followed by P2Y12 inhibitor monotherapy is as effective as a 12-month course with fewer bleeding events. PubMed, Scopus, and Cochrane Central were searched for randomized controlled trials of ACS patients comparing dual antiplatelet therapy (DAPT) for 1 to 3 months followed by a P2Y12 inhibitor to 12-month DAPT. Quality assessment was performed with the Cochrane Collaboration risk of bias assessment tool. Five randomized clinical trials were included, with a total of 18,046 participants.

Source: The American Journal of Cardiology - May 25, 2021 Category: Cardiology Authors: Leonardo Knijnik, Marcelo Fernandes, Manuel Rivera, Rhanderson Cardoso, Abhinav Goyal, Henry Liberman, Laurence S. Sperling, Michael C. McDaniel Source Type: research