Is Uncontrolled Diabetes Mellitus Associated with Incidence of Complications After Posterior Instrumented Lumbar Fusion? A National Claims Database Analysis

Clin Orthop Relat Res. 2021 May 20. doi: 10.1097/CORR.0000000000001823. Online ahead of print.ABSTRACTBACKGROUND: Previous research has shown that diabetes mellitus (DM) is associated with postoperative complications, including surgical site infections (SSIs). However, evidence for the association between diabetes control and postoperative complications in patients with DM is mixed. Prior studies relied on a single metric for defining uncontrolled DM, which does not account for glycemic variability, and it is unknown whether a more comprehensive assessment of diabetes control is associated with postoperative complications.QUESTIONS/PURPOSES: (1) Is there a difference in the incidence of SSI after lumbar spine fusion in patients with uncontrolled DM, defined with a comprehensive assessment of glycemic control, compared with patients with controlled DM? (2) Is there a difference in the incidence of other select postoperative complications after lumbar spine fusion in patients with uncontrolled DM compared with patients with controlled DM? (3) Is there a difference in total reimbursements between these groups?METHODS: We used the PearlDiver Patient Records Database, a national administrative claims database that provides access to the full continuum of perioperative care. We included 46,490 patients with DM undergoing posterior lumbar fusion with instrumentation. Patients were required to be continuously enrolled in the database for at least 1 year before and 90 days after the i...
Source: Clinical Orthopaedics and Related Research - Category: Orthopaedics Authors: Source Type: research

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ConclusionVariations of pH occurred in the majority (79.7%) of patients admitted with COVID-19. The patients experienced all the type of acid –base disorders, notably metabolic and respiratory alkalosis were the most common alterations in this group of patients.
Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research
Your heart rate is a measurement of the number of times per minute that your heart contracts or beats. Monitoring your heart rate is useful for tracking fitness and managing the risk factors of heart and circulatory diseases like diabetes. So, how do you measure your heart rate and what is a healthy heart rate?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
ConclusionsIn our local experience, robotic off-pump HCR in women was as safe as conventional ONCAB and OPCAB and may further improve postoperative outcomes when performed frequently by a dedicated team, producing better perioperative outcomes without compromising survival in the long run.
Source: Journal of Cardiac Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: ORIGINAL ARTICLE Source Type: research
ConclusionWe observed a significant reduction in mortality during the period 2008 –2017 in diabetes either as underlying cause of death or when all mentions of diabetes in the death certificate were considered.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research
The objective of this study is to explore the relationship between serum 25 ‐hydroxyvitamin-D(25-(OH)2D3) level and sweat function in patients with type 2 diabetes mellitus (T2DM).MethodsA cross-sectional study of 1021 patients with T2DM who underwent 25-(OH)2D3 level detections and sweat function tests was carried out. These individuals were divided into deficient groups (n = 154 cases), insufficient groups (n = 593 cases) and sufficient groups (n = 274 cases). Spearman correlation analysis and multivariate stepwise linear regression analysis were implemented to determine the as...
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research
AbstractPurposeAlthough the gut microbiota (GM) are associated with various diseases, their role in gestational diabetes mellitus (GDM) remains uncharacterized. Further study is urgently needed to expose the real relationship between GM and GDM.MethodsWe performed a prospective study in 33 pregnant Chinese individuals [15, GDM; 18, normal glucose tolerance (NGT)] to observe the fecal microbiota by 16S rRNA gene amplicon sequencing at 24 –28 weeks of gestational age after a standard 75 g oral glucose tolerance test. Linear regression analysis was employed to assess the relationships between the GM and GDM cl...
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research
TYPE 1 diabetes causes blood sugar levels to become too high and can cause severe damage to the body if left untreated. Blood tests are the best way to diagnose suspected diabetes, but there are a few unusual symptoms that could be an early warning sign.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
The objectives of this study were (1) to characterize the effect of T2DM on microdamage quantity and morphology in cancellous bone, and (2) relate the accumulation of microdamage to the cancellous microarchitecture. Cancellous specimens from the femoral neck were collected during total hip arthroplasty (T2DM: n  = 22, age = 65+ 9  years, HbA1c = 7.00+ 0.98%; Non-DM: n  = 25, age = 61+ 8  years, HbA1c = 5.50+ 0.4%), compressed to 3% strain, stained with lead uranyl acetate to isolate microdamage, and scanned with micro-computed tomography. Individual ...
Source: Journal of Bone and Mineral Research - Category: Orthopaedics Authors: Tags: Original Article Source Type: research
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Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Source: AAP Grand Rounds - Category: Pediatrics Source Type: research
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