Interleukin-1 β-induced matrix metalloproteinase-3 via ERK1/2 pathway to promote mesenchymal stem cell migration

In conclusion, we have found that IL-1β induces the expression of MMP-3 through ERK1/2, JNK, p38 MAPK and Akt signaling pathways to enhance the migration of hUCMSCs. These results provide further understanding of the mechanisms in IL-1β-induced hUCMSCs migration to injury sites.
Source: PLoS One - Category: Biomedical Science Authors: Source Type: research