Obesity decreases the EC50 of epidural ropivacaine when combined with dexmedetomidine for labor analgesia

CONCLUSION: : Patients with antepartum obese may require decreased ropivacaine concentration for epidural labor analgesia when co-administered with 0.5-μg/mL dexmedetomidine.PMID:33980116 | DOI:10.1080/17512433.2021.1929924

Source: Expert Review of Clinical Pharmacology - May 13, 2021 Category: Drugs & Pharmacology Authors: Xiaojun Chen Meng Cai Xiaofeng Lei Jin Yu Source Type: research