Effect of Experimental Fanconi Syndrome on Tubular Reabsorption of Lithium in Rats

This study represents that the tubular reabsorption of lithium was impaired to the same degree with glomerular filtration in rats with experimental Fanconi syndrome and that the dysfunction of the tubular reabsorption of glucose and phosphate was more severe. It is possible that Fanconi syndrome inhibited the reabsorption of lithium at the proximal tubule and facilitated the reabsorption of lithium from the loop of Henle to the collecting duct.Pharmacology
Source: Pharmacology - Category: Drugs & Pharmacology Source Type: research