Intrinsic exercise capacity induces divergent vascular plasticity via arachidonic acid-mediated inflammatory pathways in female rats

In conclusion, LCR display low-grade chronic inflammation via increased COX activity. These results provide mechanistic clues as to why lower intrinsic aerobic capacity correlates with a predisposition to risk of vascular disease. Conversely, being born with higher intrinsic aerobic capacity is a significant factor for improved vascular physiology in female rats.PMID:33872803 | DOI:10.1016/j.vph.2021.106862

Source: Vascular Pharmacology - April 19, 2021 Category: Drugs & Pharmacology Authors: Vaishnavi Aradhyula Emily Waigi Nicole R Bearss Jonnelle M Edwards Bina Joe Cameron G McCarthy Lauren B Koch Camilla F Wenceslau Source Type: research