Human Schlafen 5 Inhibits Proliferation and Promotes Apoptosis in Lung Adenocarcinoma via the PTEN/PI3K/AKT/mTOR Pathway

In conclusion, these suggest that human SLFN5 plays inhibitory roles in LUAC progression through the PTEN/PI3K/AKT/mTOR pathway, providing a potential target for developing drugs for lung cancer therapy in the future.PMID:33860045 | PMC:PMC8009730 | DOI:10.1155/2021/6628682

Source: Biomed Res - April 16, 2021 Category: Research Authors: Xuefeng Gu Li Zhou Lei Chen Huiqing Pan Rui Zhao Weiwei Guang Guoqing Wan Peng Zhang Dingsheng Liu Li-Li Deng Weiming Zhao Changlian Lu Source Type: research