Orphan nuclear receptor ERR-{gamma} regulates hepatic FGF23 production in acute kidney inȷury [Medical Sciences]

Fibroblast growth factor 23 (FGF23), a hormone generally derived from bone, is important in phosphate and vitamin D homeostasis. In acute kidney injury (AKI) patients, high-circulating FGF23 levels are associated with disease progression and mortality. However, the organ and cell type of FGF23 production in AKI and the molecular mechanism...

Source: Proceedings of the National Academy of Sciences - April 14, 2021 Category: Science Authors: Kamalakannan Radhakrishnan, Yong–Hoon Kim, Yoon Seok Jung, Don–Kyu Kim, Soon–Young Na, Daeȷin Lim, Dong Hun Kim, Jina Kim, Hyung–Seok Kim, Hyon E. Choy, Sung Jin Cho, In–Kyu Lee, Şamil Ayvaz, Stefanie Nittka, Da Tags: Medical Sciences Biological Sciences Source Type: research