Farnesoid X receptor via Notch1 directs asymmetric cell division of Sox9+ cells to prevent the development of liver cancer in a mouse model

Asymmetrical cell division (ACD) maintains the proper number of stem cells to ensure self-renewal. The rate of symmetric division increases as more cancer stem cells (CSCs) become malignant; however, the signa...

Source: Stem Cell Research and Therapy - April 12, 2021 Category: Stem Cells Authors: Mi Chen, Chenxia Lu, Hanwen Lu, Junyi Zhang, Dan Qin, Shenghui Liu, Xiaodong Li and Lisheng Zhang Tags: Research Source Type: research