Tropism of mesenchymal stem cell toward CD133+ stem cell of glioblastoma in vitro and promote tumor proliferation in vivo
Previous studies have demonstrated remarkable tropism of mesenchymal stem cells (MSCs) toward malignant gliomas, making these cells a potential vehicle for delivery of therapeutic agents to disseminated gliobl... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - November 9, 2018 Category: Stem Cells Authors: Lorena Favaro Pavon, Tatiana Tais Sibov, Andrea Vieira de Souza, Edgar Ferreira da Cruz, Suzana M. F. Malheiros, Francisco Romero Cabral, Jean Gabriel de Souza, Pamela Boufleur, Daniela Mara de Oliveira, Silvia Regina Caminada de Toledo, Luciana C. Marti, Tags: Research Source Type: research

Combination therapy of human bone marrow –derived mesenchymal stem cells and minocycline improves neuronal function in a rat middle cerebral artery occlusion model
The positive effects of human bone marrow –derived mesenchymal stem cells (hBM-MSCs) and minocycline on ischemic stroke models have been well described through numerous studies. The aim of this study was to eva... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - November 9, 2018 Category: Stem Cells Authors: Dong Young Cho and Sin-Soo Jeun Tags: Research Source Type: research

Key genes and integrated modules in hematopoietic differentiation of human embryonic stem cells: a comprehensive bioinformatic analysis
The generation of hematopoietic stem cells (HSCs) and blood cells from human embryonic stem cells (hESCs) is a major goal for regenerative medicine; however, the differentiation mechanisms are largely undefine... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - November 8, 2018 Category: Stem Cells Authors: Pengfei Li, Mengyao Wu, Qiwang Lin, Shu Wang, Tong Chen and Hua Jiang Tags: Research Source Type: research

In vitro MSC function is related to clinical reaction in vivo
We recently demonstrated that intracellular xenogen-contaminated autologous MSCs (FBS) and non-xenogen-contaminated allogeneic (ALLO) MSCs caused an adverse clinical response after repeated intra-articular inj... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - November 8, 2018 Category: Stem Cells Authors: Aileen L. Rowland, Jiajie Jessica Xu, Amanda Jo Joswig, Carl A. Gregory, Douglas F. Antczak, Kevin J. Cummings and Ashlee E. Watts Tags: Research Source Type: research

A review: therapeutic potential of adipose-derived stem cells in cutaneous wound healing and regeneration
As the most important barrier for the human body, the skin often suffers from acute and chronic injuries, especially refractory wounds, which seriously affect the quality of life of patients. For these refract... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - November 8, 2018 Category: Stem Cells Authors: Peng Li and Xiutian Guo Tags: Review Source Type: research

Pamidronate decreases bilirubin-impaired cell death and improves dentinogenic dysfunction of stem cells from human deciduous teeth
Hyperbilirubinemia that occurs in pediatric liver diseases such as biliary atresia can result in the development of not only jaundice in the brain, eyes, and skin, but also tooth abnormalities including green ... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - November 8, 2018 Category: Stem Cells Authors: Haruyoshi Yamaza, Soichiro Sonoda, Kazuaki Nonaka, Toshio Kukita and Takayoshi Yamaza Tags: Research Source Type: research

Fat extract promotes angiogenesis in a murine model of limb ischemia: a novel cell-free therapeutic strategy
The proangiogenic capacity of adipose tissue and its derivatives has been demonstrated in a variety of studies. The paracrine mechanism of the cellular component is considered to play a critical role in the re... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - November 8, 2018 Category: Stem Cells Authors: Ziyou Yu, Yizuo Cai, Mingwu Deng, Dong Li, Xiangsheng Wang, Hongjie Zheng, Yuda Xu, Wei Li and Wenjie Zhang Tags: Research Source Type: research

Identifying deer antler uhrf1 proliferation and s100a10 mineralization genes using comparative RNA-seq
Deer antlers are bony structures that re-grow at very high rates, making them an attractive model for studying rapid bone regeneration. (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 31, 2018 Category: Stem Cells Authors: Dai Fei Elmer Ker, Dan Wang, Rashmi Sharma, Bin Zhang, Ben Passarelli, Norma Neff, Chunyi Li, William Maloney, Stephen Quake and Yunzhi Peter Yang Tags: Research Source Type: research

Human cardiac stem cells inhibit lymphocyte proliferation through paracrine mechanisms that correlate with indoleamine 2,3-dioxygenase induction and activity
Transplantation of allogeneic human cardiac/stem progenitor cells (hCSCs) is currently being tested in several phase I/II clinical trials as a novel and promising therapy for restoration of myocardial tissue f... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 25, 2018 Category: Stem Cells Authors: Maria J Sebasti ão, Ramón Menta, Margarida Serra, Itziar Palacios, Paula M Alves, Belén Sanchez, Olga DelaRosa, Wilfried Dalemans, Eleuterio Lombardo and Patrícia Gomes-Alves Tags: Short report Source Type: research

Correction to: PARP1 inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD+ levels and increasing SIRT1 activity
The original article [1] contains an error regarding the erroneous inclusion of 3 μl as a parameter in the x-axis of Fig. 2c; the correct version of Fig. 2c can instead be seen below. (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 25, 2018 Category: Stem Cells Authors: Siyuan Zha, Zhen Li, Qing Cao, Fei Wang and Fang Liu Tags: Correction Source Type: research

Correction to: Rat limbal niche cells can induce transdifferentiation of oral mucosal epithelial cells into corneal epithelial-like cells in vitro
The original article [1] contains an error in Fig. 5e whereby the immunofluorescence of ΔNp63α in the ME group is incorrectly presented; thus, the corrected figure is shown ahead. (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 25, 2018 Category: Stem Cells Authors: X. Y. Zhao, H. T. Xie, C. Y. Duan, J. Li and M. C. Zhang Tags: Correction Source Type: research

Clinical efficiency of bone marrow mesenchymal stem cell implantation for osteonecrosis of the femoral head: a matched pair control study with simple core decompression
This study compa... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 25, 2018 Category: Stem Cells Authors: Joon Soon Kang, Young Ju Suh, Kyoung Ho Moon, Jun Sung Park, Tae Hoon Roh, Myung Hoon Park and Dong Jin Ryu Tags: Research Source Type: research

Establishment of a rapid and footprint-free protocol for differentiation of human embryonic stem cells into pancreatic endocrine cells with synthetic mRNAs encoding transcription factors
Transplantation of pancreatic β cells generated in vitro from pluripotent stem cells (hPSCs) such as embryonic stem cells (ESCs) or induced pluripotent stem cells (iPSCs) has been proposed as an alternative th... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 25, 2018 Category: Stem Cells Authors: Hideomi Ida, Tomohiko Akiyama, Keiichiro Ishiguro, Sravan K. Goparaju, Yuhki Nakatake, Nana Chikazawa-Nohtomi, Saeko Sato, Hiromi Kimura, Yukihiro Yokoyama, Masato Nagino, Minoru S. H. Ko and Shigeru B. H. Ko Tags: Research Source Type: research

Preconditioning of bone marrow-derived mesenchymal stem cells highly strengthens their potential to promote IL-6-dependent M2b polarization
During the last decade, mesenchymal stem cells (MSCs) have gained much attention in the field of regenerative medicine due to their capacity to differentiate into different cell types and to promote immunosupp... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 25, 2018 Category: Stem Cells Authors: Denise Philipp, Laura Suhr, Thorsten Wahlers, Yeong-Hoon Choi and Adnana Paunel-G örgülü Tags: Research Source Type: research

Improving hematopoietic recovery through modeling and modulation of the mesenchymal stromal cell secretome
Efficient and sustained hematopoietic recovery after hematopoietic stem cell or bone marrow transplantation is supported by paracrine signaling from specific subpopulations of mesenchymal stromal cells (MSCs).... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 24, 2018 Category: Stem Cells Authors: Frances D. Liu, Kimberley Tam, Novalia Pishesha, Zhiyong Poon and Krystyn J. Van Vliet Tags: Research Source Type: research

Tcf7l1 directly regulates cardiomyocyte differentiation in embryonic stem cells
The T-cell factor/lymphoid enhancer factor (TCF/LEF) family protein Tcf7l1 is highly abundant in embryonic stem cells (ESCs), regulating pluripotency and preparing epiblasts for further differentiation. Defect... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 11, 2018 Category: Stem Cells Authors: Rui Liang and Yu Liu Tags: Short report Source Type: research

Schwann cell-like differentiated adipose stem cells promote neurite outgrowth via secreted exosomes and RNA transfer
In this study we investigated the importance of exosomes, extracellular vesicles release... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 11, 2018 Category: Stem Cells Authors: Rosanna C Ching, Mikael Wiberg and Paul J Kingham Tags: Research Source Type: research

Short-term physiological hypoxia potentiates the therapeutic function of mesenchymal stem cells
In the bone marrow, MSCs reside in a hypoxic milieu (1 –5% O2) that is thought to preserve their multipotent state. Typically, in vitro expansion of MSCs is performed under normoxia (~ 21% O2), a process that has ... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 11, 2018 Category: Stem Cells Authors: Ben Antebi, Luis A Rodriguez II, Kerfoot P Walker III, Amber M Asher, Robin M Kamucheka, Lucero Alvarado, Arezoo Mohammadipoor and Leopoldo C Cancio Tags: Research Source Type: research

Correction to: Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1
The original article [1] contains a number of small errors which the authors would like to clarify: (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 7, 2018 Category: Stem Cells Authors: Bushra Memon, Manale Karam, Sara Al-Khawaga and Essam M. Abdelalim Tags: Correction Source Type: research

Correction to: Treatment of periodontal intrabony defects using autologous periodontal ligament stem cells: a randomized clinical trial
The original article [1] contains a major error carried across the captions of Tables 1, 2, and 3. In each table caption, the data were expressed as “mean ± standard deviation (SD)”; unfortunately, the authors... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 7, 2018 Category: Stem Cells Authors: Fa-Ming Chen, Li-Na Gao, Bei-Min Tian, Xi-Yu Zhang, Yong-Jie Zhang, Guang-Ying Dong, Hong Lu, Qing Chu, Jie Xu, Yang Yu, Rui-Xin Wu, Yuan Yin, Songtao Shi and Yan Jin Tags: Correction Source Type: research

Correction to: The role of fibrinolysis inhibition in engineered vascular networks derived from endothelial cells and adipose-derived stem cells
The original article [1] contains numerous value errors in the graphs in Fig. 2b regarding the markers describing the values for total tubule length and mean tubule length without aprotinin at 2.5 mg/ml concen... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 7, 2018 Category: Stem Cells Authors: Severin M ühleder, Karoline Pill, Mira Schaupper, Krystyna Labuda, Eleni Priglinger, Pablo Hofbauer, Verena Charwat, Uwe Marx, Heinz Redl and Wolfgang Holnthoner Tags: Correction Source Type: research

Correction to: Culture of mesenchymal stem cells derived from equine synovial membrane in alginate hydrogel microcapsules
The original article [1] contained a minor error regarding the mean diameter of the alginate microcapsules described in relation to Fig. 4 in the Results section. The microcapsules had an actual mean diameter ... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 7, 2018 Category: Stem Cells Authors: Vitor Hugo Santos, Jo ão Pedro Hübbe Pfeifer, Jaqueline Brandão de Souza, Betsabéia Heloisa Gentilha Milani, Rogério Antonio de Oliveira, Marjorie Golim Assis, Elenice Deffune, Andrei Moroz and Ana Liz Garcia Alves Tags: Correction Source Type: research

The therapeutic potential of bone marrow mesenchymal stem cells in premature ovarian failure
With the development of regenerative medicine, a variety of mesenchymal stem cells (MSCs) are increasingly considered for the treatment of premature ovarian failure (POF). Reportedly, bone marrow-derived MSCs ... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 4, 2018 Category: Stem Cells Authors: Yantao He, Dongmei Chen, Lingling Yang, Qiaoni Hou, Huiming Ma and Xian Xu Tags: Review Source Type: research

A robust cell culture system for large scale feeder cell-free expansion of human breast epithelial progenitors
Normal human breast epithelial cells are maintained by the proliferation and differentiation of different human breast epithelial progenitors (HBEPs). However, these progenitor subsets can only be obtained at ... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - October 4, 2018 Category: Stem Cells Authors: Sumanta Chatterjee, Pratima Basak, Edward Buchel, Leigh C. Murphy and Afshin Raouf Tags: Short report Source Type: research

Induction of bone marrow-derived cells myogenic identity by their interactions with the satellite cell niche
Skeletal muscle regeneration is possible thanks to unipotent stem cells, which are satellite cells connected to the myofibers. Populations of stem cells other than muscle-specific satellite cells are considere... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - September 27, 2018 Category: Stem Cells Authors: Kamil Kowalski, Matthieu Dos Santos, Pascal Maire, Maria A. Ciemerych and Edyta Brzoska Tags: Research Source Type: research

Organ culture of seminiferous tubules using a modified soft agar culture system
In-vitro spermatogenesis in mammalian species is considered an important topic in reproductive biology. New strategies for achieving a complete version of spermatogenesis ex vivo have been conducted using an o... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - September 26, 2018 Category: Stem Cells Authors: Keykavos Gholami, Gholamreza Pourmand, Morteza Koruji, Sepideh Ashouri and Mehdi Abbasi Tags: Research Source Type: research

Astrocyte-based cell therapy: new hope for amyotrophic lateral sclerosis patients?
Amyotrophic lateral sclerosis (ALS) is a fatal paralytic disease with no cure or treatment to stop disease progression. Because ALS represents an urgent unmet medical need, a significant number of therapeutics... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - September 26, 2018 Category: Stem Cells Authors: Luis Barbeito Tags: Commentary Source Type: research

Osteogenesis and aging: lessons from mesenchymal stem cells
Aging is a high risk factor for the development of osteoporosis, a multifactorial age-related progressive disease characterized by reduced bone mass and increased risk of fractures. At the cellular level, the ... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - September 26, 2018 Category: Stem Cells Authors: Arantza Infante and Clara I. Rodr íguez Tags: Review Source Type: research

Development and validation of broad-spectrum magnetic particle labelling processes for cell therapy manufacturing
Stem cells are increasingly seen as a solution for many health challenges for an ageing population. However, their potential benefits in the clinic are currently curtailed by technical challenges such as high ... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - September 26, 2018 Category: Stem Cells Authors: Richard Harrison, Hilda Anaid Lugo Leija, Stephanie Strohbuecker, James Crutchley, Sarah Marsh, Chris Denning, Alicia El Haj and Virginie Sottile Tags: Research Source Type: research

Intraurethral co-transplantation of bone marrow mesenchymal stem cells and muscle-derived cells improves the urethral closure
Cell therapy constitutes an attractive alternative to treat stress urinary incontinence. Although promising results have been demonstrated in this field, the procedure requires further optimization. The most c... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - September 21, 2018 Category: Stem Cells Authors: Anna Burdzinska, Bartosz Dybowski, Weronika Zarychta-Wi śniewska, Agnieszka Kulesza, Marta Butrym, Radoslaw Zagozdzon, Agnieszka Graczyk-Jarzynka, Piotr Radziszewski, Zdzislaw Gajewski and Leszek Paczek Tags: Research Source Type: research

Human chorionic villous mesenchymal stem/stromal cells protect endothelial cells from injury induced by high level of glucose
Mesenchymal stem/stromal cells derived from chorionic villi of human term placentae (pMSCs) protect human endothelial cells from injury induced by hydrogen peroxide (H2O2). In diabetes, elevated levels of glucose... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - September 21, 2018 Category: Stem Cells Authors: Y. S. Basmaeil, A. M. Al Subayyil, T. Khatlani, E. Bahattab, M. Al-Alwan, F. M. Abomaray, B. Kalionis, M. A. Alshabibi, A. S. AlAskar and M. H. Abumaree Tags: Research Source Type: research

Mesenchymal stem cells alleviate experimental autoimmune cholangitis through immunosuppression and cytoprotective function mediated by galectin-9
Mesenchymal stem cells (MSCs) play an anti-inflammatory role by secreting certain bioactive molecules to exert their therapeutic effects for disease treatment. However, the underlying mechanism of MSCs in chro... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - September 17, 2018 Category: Stem Cells Authors: Junyu Fan, Xiaojun Tang, Qian Wang, Zhuoya Zhang, Shufang Wu, Wenchao Li, Shanshan Liu, Genhong Yao, Hongwei Chen and Lingyun Sun Tags: Research Source Type: research

Umbilical cord tissue cryopreservation: a short review
In this review we present current evidence on the possibility of umbilical cord tissue cryopreservation for subsequent clinical use. Protocols for obtaining umbilical cord-derived vessels, Wharton ’s jelly-base... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - September 15, 2018 Category: Stem Cells Authors: Irina Arutyunyan, Timur Fatkhudinov and Gennady Sukhikh Tags: Review Source Type: research

Linking cell function with perfusion: insights from the transcatheter delivery of bone marrow-derived CD133+ cells in ischemic refractory cardiomyopathy trial (RECARDIO)
Cell therapy with bone marrow (BM)-derived progenitors has emerged as a promising therapeutic for refractory angina (RA) patients. In the present study, we evaluated the safety and preliminary efficacy of tran... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - September 14, 2018 Category: Stem Cells Authors: Beatrice Bassetti, Corrado Carbucicchio, Valentina Catto, Elisa Gambini, Erica Rurali, Alberto Bestetti, Giuseppe Gaipa, Daniela Belotti, Fabrizio Celeste, Matteo Parma, Stefano Righetti, Lorenza Biava, Maurizio Arosio, Alice Bonomi, Piergiuseppe Agostoni Tags: Research Source Type: research

Revealing cellular and molecular complexity of the central nervous system using single cell sequencing
The mammalian central nervous system (CNS) is one of the most complex systems, with thousands of cell types and subtypes with distinct and unique morphology and gene expression profiles. Based on classic histo... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - September 13, 2018 Category: Stem Cells Authors: Zhiwei Zeng, Nan Miao and Tao Sun Tags: Review Source Type: research

Skeletal muscle-derived cell implantation for the treatment of sphincter-related faecal incontinence
In an earlier pilot study with 10 women, we investigated a new approach for therapy of faecal incontinence (FI) due to obstetric trauma, involving ultrasound-guided injection of autologous skeletal muscle-deri... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - September 13, 2018 Category: Stem Cells Authors: Andrea Frudinger, Rainer Marksteiner, Johann Pfeifer, Eva Margreiter, Johannes Paede and Marco Thurner Tags: Research Source Type: research

Circular RNA CDR1as regulates osteoblastic differentiation of periodontal ligament stem cells via the miR-7/GDF5/SMAD and p38 MAPK signaling pathway
Periodontal ligament stem cells (PDLSCs) are considered as candidate cells for the regeneration of periodontal and alveolar bone tissues. Antisense to the cerebellar degeneration-related protein 1 transcript (... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - August 31, 2018 Category: Stem Cells Authors: Xiaobei Li, Yunfei Zheng, Yan Zheng, Yiping Huang, Yixin Zhang, Lingfei Jia and Weiran Li Tags: Research Source Type: research

miR-431 inhibits adipogenic differentiation of human bone marrow-derived mesenchymal stem cells via targeting insulin receptor substance 2
An understanding of the mechanism underlying adipogenic differentiation of human bone marrow-derived mesenchymal stem cells (hMSCs) will provide new therapeutic approaches for many diseases, including osteopor... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - August 30, 2018 Category: Stem Cells Authors: Yangling Wang, Lei Yang, Xiaofeng Liu, Tao Hong, Tao Wang, Aiwu Dong, Jiangxiong Li, Xiaoyuan Xu and Lingling Cao Tags: Research Source Type: research

Differentiation and transplantation of human induced pluripotent stem cell-derived otic epithelial progenitors in mouse cochlea
Inner ear hair cells as mechanoreceptors are extremely important for hearing. Defects in hair cells are a major cause of deafness. Induced pluripotent stem cells (iPSCs) are promising for regenerating inner ea... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - August 29, 2018 Category: Stem Cells Authors: Jianling Chen, Fanfan Hong, Cui Zhang, Liang Li, Cuicui Wang, Haosong Shi, Yong Fu and Jinfu Wang Tags: Research Source Type: research

Correction to: Periosteal progenitors contribute to load-induced bone formation in adult mice and require primary cilia to sense mechanical stimulation
The original article [1] contained two minor errors affecting the labelling of Fig. 3d and Figs. 6b& 6c; these errors have now been corrected in the respective figures in the original article. (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - August 28, 2018 Category: Stem Cells Authors: Emily R. Moore, Ya Xing Zhu, Han Seul Ryu and Christopher R. Jacobs Tags: Correction Source Type: research

Progress in mesenchymal stem cell –based therapy for acute liver failure
Acute liver failure is a life-threatening clinical syndrome characterized by rapid development of hepatocellular necrosis leading to high mortality and resource costs. Numerous treatment strategies for acute l... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - August 24, 2018 Category: Stem Cells Authors: Yong-Hong Wang, Dong-Bo Wu, Bing Chen, En-Qiang Chen and Hong Tang Tags: Review Source Type: research

Current status and potential challenges of mesenchymal stem cell-based therapy for malignant gliomas
Glioma, which accounts for more than 30% of primary central nervous system tumours, is characterised by symptoms such as headaches, epilepsy, and blurred vision. Glioblastoma multiforme is the most aggressive,... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - August 24, 2018 Category: Stem Cells Authors: Qing Zhang, Wei Xiang, Dong-ye Yi, Bing-zhou Xue, Wan-wan Wen, Ahmed Abdelmaksoud, Nan-xiang Xiong, Xiao-bing Jiang, Hong-yang Zhao and Peng Fu Tags: Review Source Type: research

Induced pluripotent stem cells as a tool to study brain circuits in autism-related disorders
The mammalian brain is a very complex organ containing an estimated 200 billion cells in humans. Therefore, studying human brain development has become very challenging given all the data that are available fr... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - August 23, 2018 Category: Stem Cells Authors: Aline Vitrac and Isabelle Clo ëz-Tayarani Tags: Review Source Type: research

PARP1 inhibitor (PJ34) improves the function of aging-induced endothelial progenitor cells by preserving intracellular NAD+ levels and increasing SIRT1 activity
Nicotinamide adenine dinucleotide (NAD+) is a critical molecule involved in various biological functions. Poly (ADP-ribose) polymerase 1 (PARP1) and sirtuin 1 (SIRT1) affect cellular NAD+ levels and play essentia... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - August 23, 2018 Category: Stem Cells Authors: Siyuan Zha, Zhen Li, Qing Cao, Fei Wang and Fang Liu Tags: Research Source Type: research

Novel preconditioning strategies for enhancing the migratory ability of mesenchymal stem cells in acute kidney injury
Acute kidney injury (AKI) remains a worldwide public health issue due to its increasing incidence, significant mortality, and lack of specific target-orientated therapy. Developments in mesenchymal stem cell (... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - August 23, 2018 Category: Stem Cells Authors: Lingfei Zhao, Chenxia Hu, Ping Zhang, Hua Jiang and Jianghua Chen Tags: Review Source Type: research

Endothelial progenitor cell-derived exosomes, loaded with miR-126, promoted deep vein thrombosis resolution and recanalization
In this report, we investigated the effect... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - August 23, 2018 Category: Stem Cells Authors: Jiacheng Sun, Zhiwei Zhang, Teng Ma, Ziying Yang, Jinlong Zhang, Xuan Liu, Da Lu, Zhenya Shen, Junjie Yang and Qingyou Meng Tags: Research Source Type: research

Correction to: Urine-derived cells for human cell therapy
The original article [1] contained a small typo affecting the co-author, Mohammed Al-Hawwas ’s name. This error has now been corrected. (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - August 22, 2018 Category: Stem Cells Authors: Nimshitha Pavathuparambil Abdul Manaph, Mohammed Al-Hawwas, Larisa Bobrovskaya, Patrick T. Coates and Xin-Fu Zhou Tags: Correction Source Type: research

A novel mutation of MSX1 in oligodontia inhibits odontogenesis of dental pulp stem cells via the ERK pathway
Tooth agenesis, one of the most common developmental anomalies, can affect the function and esthetics of patients. The aim of the present study was to identify genetic clues for familial tooth agenesis and exp... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - August 22, 2018 Category: Stem Cells Authors: Tianyi Xin, Ting Zhang, Qian Li, Tingting Yu, Yunyan Zhu, Ruili Yang and Yanheng Zhou Tags: Research Source Type: research

Therapeutic potential of stromal cells of non-renal or renal origin in experimental chronic kidney disease
Mesenchymal stromal cell (MSC)-based therapy is a promising strategy for preventing the progression of chronic kidney disease (CKD), with the potential to induce tissue regeneration. In search of the best cell... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - August 14, 2018 Category: Stem Cells Authors: Cinzia Rota, Marina Morigi, Domenico Cerullo, Martino Introna, Ornella Colpani, Daniela Corna, Chiara Capelli, Ton J. Rabelink, Danielle G. Leuning, Daniela Rottoli, Ariela Benigni, Carlamaria Zoja and Giuseppe Remuzzi Tags: Research Source Type: research

Inhibition of mTORC1 signaling protects kidney from irradiation-induced toxicity via accelerating recovery of renal stem-like cells
Irradiation-induced kidney damage is inevitable during radiotherapeutic practice, which limits effective radiotherapy doses on tumor treatment. In the present study, the role of mTOR complex 1 (mTORC1) signali... (Source: Stem Cell Research and Therapy)
Source: Stem Cell Research and Therapy - August 14, 2018 Category: Stem Cells Authors: Lijian Shao, Wuping Yang, Rui Xu, Shuqin Zhu, Yanqiu Huang, Huan Li, Xincheng Wu, Mengzhen Yue, Xiaoliang Xiong, Xiaowen Chen, Bohai Kuang, Guangqin Fan, Qingxian Zhu and Huihong Zeng Tags: Research Source Type: research