Harnessing psilocybin: antidepressant-like behavioral and synaptic actions of psilocybin are independent of 5-HT2R activation in mice [Neuroscience]

Depression is a widespread and devastating mental illness and the search for rapid-acting antidepressants remains critical. There is now exciting evidence that the psychedelic compound psilocybin produces not only powerful alterations of consciousness, but also rapid and persistent antidepressant effects. How psilocybin exerts its therapeutic actions is not known, but...

http://www.pnas.org/content/118/17/e2022489118.short?rss=1

Source: Proceedings of the National Academy of Sciences - April 13, 2021 Category: Science Authors: Natalie Hesselgrave, Timothy A. Troppoli, Andreas B. Wulff, Anthony B. Cole, Scott M. Thompson Tags: Neuroscience Biological Sciences Source Type: research