Design, synthesis and molecular modeling studies of novel mesalamine linked coumarin for treatment of inflammatory bowel disease

In conclusion, Mesalamine-coumarin derivative reduces colonic damage in acetic acid induced ulcerative colitis in rat model, and therefore may prove to be effective in the management of IBD.PMID:33839254 | DOI:10.1016/j.bmcl.2021.128029

Source: Molecular Medicine - April 11, 2021 Category: Molecular Biology Authors: Biswabhusan Rath Faizan Abul Qais Randeep Patro Sujata Mohapatra Tripti Sharma Source Type: research