A novel ORF-1a based SARS-CoV-2 RT-PCR assay to resolve inconclusive samples

The striking difference between previous SARS-CoV/MERS-CoV outbreaks and the ongoing SARS-CoV-2 pandemic is the increased contagious nature of the latter (Yang et al., 2020). This has resulted in over 100 million SARS-CoV-2 infections globally and ∼2.2 million deaths to date (WHO COVID-19 Dashboard, 2021). India bears the second largest burden of infected individuals with 10 million infections and over 150,000 deaths so far (ICMR COVID-19 Testing Status, 2021). Efficient and rapid diagnosis is critical to optimal management of disease sprea d as well as clinical management of COVID-19.

https://www.ijidonline.com/article/S1201-9712(21)00317-9/fulltext?rss=yes

Source: International Journal of Infectious Diseases - April 10, 2021 Category: Infectious Diseases Authors: Ketki Jawade, Akhauri Yash Sinha, Sharad Bhagat, Shilpa Bhowmick, Bhagyashree Chauhan, Snehal Kaginkar, Harsha Palav, Nandini Kasarpalkar, Pratik Devadiga, Kalyani Karandikar, Sachee Agarwal, Jayanthi Shastri, Kiran Munne, Vikrant M. Bhor, Smita D. Mahale Source Type: research