APBI versus ultra APBI in the elderly with low-risk breast cancer: a comparative analysis of oncological outcome and late toxicity

Aim: Accelerated partial breast irradiation (APBI) represents a validated technique for low-risk breast cancer. Recently, ultra APBI (uAPBI) using fewer than 5 fractions were described in literature. We compared clinical outcome and late toxicity after APBI or uAPBI in the elderly.Material/methods: Two cohorts of elderly ( ≥ 70 years) low-risk breast cancer treated with APBI (interstitial brachytherapy) were retrospectively analyzed. A total dose of 34Gy/10f (APBI) or 16Gy/1f (uAPBI) was delivered from 2004 to 2012 and from 2013 to 2018 respectively.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Source Type: research