Effects of Subthalamic Deep Brain Stimulation With Different Frequencies in a Parkinsonian Rat Model

ConclusionSTN ‐HFS (130 Hz) and sham operation for one week can significantly improve the exercise performance of PD rats. The exercise performance of PD rats in LFS group (30 Hz) is worse compared with HFS group (130 Hz). HFS plays a role in neuroprotection and improvement of exercise performance of PD rats. M oreover, DTI can be used as an effective technique to assess the therapeutic effects and severity of PD.

Source: Neuromodulation: Technology at the Neural Interface - February 18, 2021 Category: Biotechnology Authors: Zhimin Li, Yi Guo, Xinjie Bao, Jianfeng Lei, Zhiwei Shen, Xin Wang, Luming Li, Yongning Li, Renzhi Wang Tags: Basic Research Source Type: research