Overall Efficacy and Safety of Safinamide in Parkinson ’s Disease: A Systematic Review and a Meta-analysis

ConclusionOverall, safinamide is effective in PDwMF patients takingl-dopa both at 100 and 50 mg daily. Evidence for efficacy in early PD is limited. Further trials are needed to better evaluate the anti-dyskinetic properties of safinamide.
Source: Clinical Drug Investigation - Category: Drugs & Pharmacology Source Type: research