Xylene delays the development of Leydig cells in pubertal rats by inducing reactive oxidative species

In conclusion, xylene exposure may disrupt the development of pubertal Leydig cells by increasing reactive oxygen species production and reducing the expression of GSK-3β, ERK1/2, AKT1, and SIRT1.PMID:33662507 | DOI:10.1016/j.tox.2021.152740

Source: Toxicology - March 4, 2021 Category: Toxicology Authors: Qiqi Zhu Songyi Zhou Zina Wen Huitao Li Bingwu Huang Yier Chen Xiaoheng Li Han Lin Yiyan Wang Ren-Shan Ge Source Type: research