Circular RNA circVAPA promotes chemotherapy drug resistance in gastric cancer progression by regulating miR-125b-5p/STAT3 axis

CONCLUSION: CircVAPA promotes chemotherapy resistance and malignant progression in GC by miR-125b-5p/STAT3 signaling. Our findings present novel insights into the mechanism by which circVAPA regulates chemotherapy resistance of GC cells. CircVAPA and miR-125b-5p may be considered as the potential targets for GC therapy.PMID:33642823 | PMC:PMC7896438 | DOI:10.3748/wjg.v27.i6.487
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Source Type: research