Faecal immunochemical testing (FIT): Sources of result variation based on three years of routine testing of symptomatic patients in English primary care

Discussion: The FIT immunoassay evaluated is capable of detecting faecal Hb at concentrations well below the DG30 threshold of 10 µg/g and is suitable for application in this context. The greatest practical challenge to FIT performance is reproducible sampling, the pre-analytical step associated with most variability. Further research should focus on reducing sampling variability, particularly as post COVID-19 guidance recommends greater FIT utilisation.PMID:33627037 | DOI:10.1080/09674845.2021.1896204

Source: British Journal of Biomedical Science - February 25, 2021 Category: Laboratory Medicine Authors: T James B D Nicholson R Marr M Paddon J E East S Justice J L Oke B Shine Source Type: research