Steerable3D: An ImageJ plugin for neurovascular enhancement in 3-D segmentation

The segmentation of vascular networks (VNs) in the central nervous system (CNS) is of crucial importance for clinical and pre-clinical image processing applications (see, e.g., [1] for a review on this subject). In particular, the three-dimensional (3-D) analysis (determination of crucial parameters such as density, distribution and continuity of vessels) of the VN (including its smallest capillaries), is one of the key issues in neurodegenerative diseases, such as multiple sclerosis [2 –4], where pathologic neurovascular alterations have been regarded as a key process [2,3].

Source: Physica Medica: European Journal of Medical Physics - January 17, 2021 Category: General Medicine Authors: Paolo Miocchi, Alejandra Sierra, Laura Maugeri, Eleonora Stefanutti, Ali Abdollahzadeh, Fabio Mangini, Marta Moraschi, Inna Bukreeva, Lorenzo Massimi, Francesco Brun, Jussi Tohka, Olli Gr öhn, Alberto Mittone, Alberto Bravin, Charles Nicaise, Federico Gi Tags: Technical note Source Type: research