Synthesis and Immunological Evaluation of the Unnatural β-linked Mucin-1 Thomsen-Friedenreich Conjugate

Org. Biomol. Chem., 2021, Accepted Manuscript DOI: 10.1039/D1OB00007A, PaperXuanjun Wu, Hunter McFall-Boegeman, Zahra Rashidijahanabad, Kunli Liu, Christian Pett, Jin Yu, Manuel Schorlemer, Sherif Ramadan, Sandra Behren, Ulrika Westerlind, Xuefei Huang MUC1 glycopeptides are attractive antigens for anti-cancer vaccine development. One potential drawback in using the native MUC1 glycopeptide for vaccine design is the instability of the O-glycosyl linkage between the... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Organic and Biomolecular Chemistry - February 25, 2021 Category: Molecular Biology Authors: Xuanjun Wu Source Type: research