Low Reinfection Rates But a High Rate of Complications in THA for Infection Sequelae in Childhood: A Systematic Review

CONCLUSION: In THAs for sequelae of childhood septic arthritis, reinfections were uncommon, whereas generally, infection rates were slightly higher than those reported for conventional primary THAs. However, the duration of follow-up might have been insufficient to identify all patients in whom infections later developed, and the available data were not adequate to precisely detect the minimum quiescent period to avoid reinfections. Moreover, the studies in this systematic review were retrospective, and selection bias, transfer bias, and assessment bias likely influenced our findings. The general effect of these biases is to cause an underestimation of the harms of the intervention. Complications, especially intraoperative fracture and nerve palsy, were common in patients with the most-severe infections. Further data on this topic are needed, ideally from multicenter or registry studies with even longer follow-up durations.LEVEL OF EVIDENCE: Level IV, therapeutic study.PMID:33617159 | DOI:10.1097/CORR.0000000000001607

Source: Clinical Orthopaedics and Related Research - February 22, 2021 Category: Orthopaedics Authors: Rocco D'Apolito Guido Bandettini Gregorio Rossi Filippo Piana Jacquot Luigi Zagra Source Type: research