Enhancement of Transamniotic Stem Cell Therapy for Spina Bifida by Genetic Engineering of Donor Mesenchymal Stem Cells with an Fgf2 Transgene

We examined whether engineered overexpression of fibroblast growth factor-2 (Fgf2) in donor mesenchymal stem cells (MSCs) could enhance spina bifida coverage induced by transamniotic stem cell therapy (TRASCET).

https://www.jpedsurg.org/article/S0022-3468(21)00170-6/fulltext?rss=yes

Source: Journal of Pediatric Surgery - February 23, 2021 Category: Surgery Authors: Stefanie P Lazow, Daniel F Labuz, Ina Kycia, David Zurakowski, Dario O Fauza Source Type: research