Expansion of alternative autoantibodies does not follow the evolution of anti ‐citrullinated protein antibodies in preclinical rheumatoid arthritis ‐ An analysis in at‐risk first‐degree relatives

ConclusionWhile alternative autoimmunity and ANA positivity is widely prevalent in FN population, including asymptomatic, seronegative FDR, expansion of alternative autoimmunity in FDR does not occur in parallel to ACPA expansion and is restricted to established RA patients.

Source: Arthritis and Rheumatology - February 4, 2021 Category: Rheumatology Authors: Vidyanand Anaparti, Irene Smolik, Xiaobo Meng, Liam O ’Neil, Mackenzie A. Jantz, Marvin J. Fritzler, Hani El‐Gabalawy Tags: FULL LENGTH Source Type: research