Neutral endopeptidase depletion decreases colon cancer cell proliferation and TGF- β1 synthesis in indirect co-cultures with normal colon fibroblasts

ConclusionsThe results suggest that the expression of NEP by colon cancer cells is essential for their proliferation and TGF- β1 synthesis during paracrine interactions with NCFs.
Source: Clinical and Translational Oncology - Category: Cancer & Oncology Source Type: research