Interval-dependent neurotoxicity after multiple ketamine injections in late postnatal mice

ConclusionsMultiple ketamine injections induce interval-dependent, long-lasting synaptic changes and behavioral impairments. Future studies should carefully consider the dosing interval as a significant factor when studying the neurotoxic effects of multiple anesthetic exposures.
Source: Journal of Anesthesia - Category: Anesthesiology Source Type: research