Association of the Fatty Acid Amide Hydrolase C385A Polymorphism with Alcohol Use Severity and Coping Motives in Heavy-drinking Youth.

CONCLUSIONS: These findings extend previous studies by suggesting that reduced endocannabinoid metabolism may be related to heavier use of alcohol in youth, prior to the onset of chronic drinking problems. Furthermore, differences in negative reinforcement-related drinking might account in part for this association.
PMID: 33460184 [PubMed - as supplied by publisher]

Source: Alcoholism, Clinical and Experimental Research - January 18, 2021 Category: Addiction Authors: Best LM, Wardell JD, Tyndale RF, McPhee MD, Le Foll B, Kish SJ, Boileau I, Hendershot CS Tags: Alcohol Clin Exp Res Source Type: research