Increased β-site APP cleaving enzyme 1-mediated insulin receptor cleavage in type 2 diabetes mellitus with cognitive impairment.

DISCUSSION: The elevated BACE1 levels in T2DM may contribute to increasing the cognitive impairment risk through both amyloidogenesis and insulin resistance.
PMID: 33410588 [PubMed - as supplied by publisher]

Source: The Journal of Alzheimers Association - January 9, 2021 Category: Psychiatry Tags: Alzheimers Dement Source Type: research