Prospective, historically controlled study to evaluate the efficacy and safety of a new paediatric formulation of nifurtimox in children aged 0 to 17 years with Chagas disease one year after treatment (CHICO)

by Jaime Altcheh, Luis Castro, Juan C. Dib, Ulrike Grossmann, Erya Huang, Guillermo Moscatelli, Jimy Jos é Pinto Rocha, Teresa Estela Ramírez, on behalf of the CHICO Study Group Nifurtimox is a recommended treatment for Chagas disease, but data from treated children are limited. We investigated the efficacy, safety and tolerability of nifurtimox administered as divisible, dispersible 30 mg and 120 mg tablets in children with Chagas disease. In this blinded, controlled stu dy conducted January 2016–July 2018, 330 patients aged
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research